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Journal article

Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans.

Abstract:

Candida spp. are opportunistic pathogens in humans, and their systemic infections display upwards of 30% mortality in immunocompromised patients. Current mammalian model systems have certain disadvantages in that obtaining results is time consuming owing to the relatively long life spans and these results have low statistical resolution because sample sizes are usually small. We have therefore evaluated the potential of Drosophila melanogaster as an additional model system with which to disse...

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Publication status:
Published

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Publisher copy:
10.1242/dmm.006619

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Disease models and mechanisms
Volume:
4
Issue:
4
Pages:
504-514
Publication date:
2011-07-01
DOI:
EISSN:
1754-8411
ISSN:
1754-8403
Source identifiers:
138815
Language:
English
Keywords:
Pubs id:
pubs:138815
UUID:
uuid:6dd81487-5d8f-420d-9b82-863d839babc3
Local pid:
pubs:138815
Deposit date:
2012-12-19

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