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Journal article

Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy

Abstract:

Background: Transient receptor potential (TRP) receptors expressed by primary sensory neurons mediate thermosensitivity, and may play a role in sensory pathophysiology. We previously reported that human dorsal root ganglion (DRG) sensory neurons co-expressed TRPV1 and TRPV3, and that these were increased in injured human DRG. Related receptors TRPV4, activated by warmth and eicosanoids, and TRPM8, activated by cool and menthol, have been characterised i...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2377-7-11

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Publisher:
BioMed Central
Journal:
BMC Neurology More from this journal
Volume:
7
Article number:
11
Publication date:
2007-05-23
Acceptance date:
2007-05-23
DOI:
EISSN:
1471-2377
Language:
English
Keywords:
UUID:
uuid:6d85469e-7562-4c6a-a224-e060fe0385e8
Local pid:
pubs:33861
Source identifiers:
33861
Deposit date:
2012-12-19

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