Journal article
Comparative effectiveness of combined favipiravir and oseltamivir therapy versus oseltamivir monotherapy in critically ill patients with influenza virus infection
- Abstract:
-
Background A synergistic effect of combination therapy with favipiravir and oseltamivir has been reported in preclinical models of influenza. However, no data are available on the clinical effectiveness of combination therapy in severe influenza.
Methods Data from 2 separate prospective studies of influenza adults were used to compare outcomes between combination and oseltamivir monotherapy. Outcomes included rate of clinical improvement (defined a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal of Infectious Diseases Journal website
- Volume:
- 221
- Issue:
- 10
- Pages:
- 1688–1698
- Publication date:
- 2019-12-11
- Acceptance date:
- 2019-12-10
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- Pmid:
-
31822885
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1077500
- UUID:
-
uuid:6d72b63d-f5bf-487f-ac13-666f2fbe0876
- Local pid:
- pubs:1077500
- Source identifiers:
-
1077500
- Deposit date:
- 2019-12-16
Terms of use
- Copyright holder:
- Wang et al
- Copyright date:
- 2019
- Rights statement:
- © The Authors 2019. Published by Oxford University Press for the Infectious Diseases Society of America
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Oxford University Press at https://doi.org/10.1093/infdis/jiz656
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