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Two case reports of distal upper limb weakness following influenza-like illness: an emerging pattern of para-infectious myositis in adults

Abstract:
Background Myositis is a recognised complication of numerous systemic viral infections including influenza. In adults the typical pattern is characterised by myalgia and marked proximal muscle weakness in upper and lower limbs and resolves slowly over weeks rather than days.
Case presentation Here, we describe two male patients with myositis with an unusual distribution of weakness in the distal upper limbs, which both followed a flu-like illness and resolved spontaneously. Both patients had moderate elevations in creatine kinase, extensive negative serological investigations, normal nerve conduction studies and myopathic changes on electromyography.
Conclusions In the para-infectious context, myositis is an important differential of acute distal upper limb weakness. This unusual pattern of acute muscle weakness should be recognised to avoid unnecessary in treatments. Similar cases in the recent literature in male patients between the ages of 25 to 55 are reviewed and suggest an emerging pattern of para-infectious myositis.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12883-020-01821-1

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Sub department:
Clinical Neurosciences
Oxford college:
Wadham College
Role:
Author
ORCID:
0000-0002-0630-8204



Publisher:
BioMed Central
Journal:
BMC Neurology More from this journal
Volume:
20
Issue:
1
Article number:
237
Publication date:
2020-06-10
Acceptance date:
2020-06-04
DOI:
EISSN:
1471-2377
Pmid:
32522188


Language:
English
Keywords:
Pubs id:
1108858
Local pid:
pubs:1108858
Deposit date:
2021-08-10

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