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First-dose ChAdOx1 and BNT162b2 COVID-19 vaccines and thrombocytopenic, thromboembolic and hemorrhagic events in Scotland

Abstract:

Reports of ChAdOx1 vaccine–associated thrombocytopenia and vascular adverse events have led to some countries restricting its use. Using a national prospective cohort, we estimated associations between exposure to first-dose ChAdOx1 or BNT162b2 vaccination and hematological and vascular adverse events using a nested incident-matched case-control study and a confirmatory self-controlled case series (SCCS) analysis. An association was found between ChAdOx1 vaccination and idiopathic thrombocyto...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41591-021-01408-4

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Role:
Author
ORCID:
0000-0002-4101-4535
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Role:
Author
ORCID:
0000-0001-6593-9092
Publisher:
Springer Nature
Journal:
Nature Medicine More from this journal
Volume:
27
Issue:
7
Pages:
1290-1297
Publication date:
2021-06-09
Acceptance date:
2021-05-26
DOI:
EISSN:
1546-170X
ISSN:
1078-8956
Pmid:
34108714

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