Journal article icon

Journal article

Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination.

Abstract:

How melanoma acquire a metastatic phenotype is a key issue. One possible mechanism is that metastasis is driven by microenvironment-induced switching between noninvasive and invasive states. However, whether switching is a reversible or hierarchical process is not known and is difficult to assess by comparison of primary and metastatic tumors. We address this issue in a model of melanoma metastasis using a novel intravital imaging method for melanosomes combined with a reporter construct in w...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Sharrock, K More by this author
Collinson, L More by this author
Expand authors...
Journal:
Cancer research
Volume:
69
Issue:
20
Pages:
7969-7977
Publication date:
2009-10-05
DOI:
EISSN:
1538-7445
ISSN:
0008-5472
URN:
uuid:6d447f13-e2b0-43fa-90e9-3b6d36d11bd8
Source identifiers:
41381
Local pid:
pubs:41381

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP