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Stress-activated MAP kinases in chromatin and transcriptional complexes

Abstract:

Stress-activated MAP kinases (SAPKs) are activated by stressors or by certain physiological stimuli and mediate an intracellular response appropriate to the change in environment. Long-term adaptation requires reprogramming of transcription and one of the most significant actions of SAPK cascades is therefore induction of gene expression. SAPKs and their downstream kinases phosphorylate many chromatin-associated and transcription factors. Further, they can induce localised histone modificatio...

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Publisher copy:
10.1007/4735_2007_0254
Journal:
Topics in Current Genetics More from this journal
Volume:
20
Pages:
283-297
Publication date:
2008-01-01
DOI:
EISSN:
1610-6970
ISSN:
1610-2096
Language:
English
Pubs id:
pubs:202340
UUID:
uuid:6d21cc63-6715-459a-9f34-7beae4b30447
Local pid:
pubs:202340
Source identifiers:
202340
Deposit date:
2012-12-19

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