Functional connectivity in the basal ganglia network differentiates PD patients from controls.

Journal article

OBJECTIVE: To examine functional connectivity within the basal ganglia network (BGN) in a group of cognitively normal patients with early Parkinson disease (PD) on and off medication compared to age- and sex-matched healthy controls (HC), and to validate the findings in a separate cohort of participants with PD. METHODS: Participants were scanned with resting-state fMRI (RS-fMRI) at 3T field strength. Resting-state networks were isolated using independent component analysis. A BGN template wa...

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Authors: Szewczyk-Krolikowski, K; Menke, R; Rolinski, M; Duff, E; Salimi-Khorshidi, G

• Publication status: Published
• Journal: Neurology
• Volume: 83
• Issue: 3
• Pages: 208-214
• Publication date: 2014-07-01
• DOI: 10.1212/WNL.0000000000000592
• EISSN: 1526-632X
• ISSN: 0028-3878
• Language: English
• Keywords: Nerve Net; Cohort Studies; Parkinson Disease; Basal Ganglia; Aged; Humans; Aged, 80 and over; Magnetic Resonance Imaging; Female; Middle Aged; Diagnosis, Differential; Functional Neuroimaging; Male