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Estimating the sensitivity of a prostate cancer screening programme for different PSA cut-off levels: A UK case study

Abstract:

Policy decisions about prostate cancer screening require data on the natural history of histological cancers and the resulting impact of screening. However, the gold standard procedure required to identify true positive histological cancer is a full autopsy of the gland which is not possible in screening studies, leading to verification bias. We aim to estimate the sensitivity of a prostate cancer screening round (PSA result to diagnosis) relative to histological cancer.We developed a framewo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.canep.2017.12.002

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Population Health
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Cancer Epidemiology Journal website
Volume:
52
Pages:
99-105
Publication date:
2018-01-04
Acceptance date:
2017-12-03
DOI:
EISSN:
1877-783X
ISSN:
1877-7821
Pmid:
29278842
Source identifiers:
813070
Language:
English
Keywords:
Pubs id:
pubs:813070
UUID:
uuid:6cf3a05a-b60e-4b77-b93b-50f295bed2a9
Local pid:
pubs:813070
Deposit date:
2018-01-09

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