- Abstract:
-
A major discovery of recent decades has been the existence of stem cells and their potential to repair many, if not most, tissues. With the aging population, many attempts have been made to use exogenous stem cells to promote tissue repair, so far with limited success. An alternative approach, which may be more effective and far less costly, is to promote tissue regeneration by targeting endogenous stem cells. However, ways of enhancing endogenous stem cell function remain poorly defined. Inj...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 2.5MB)
-
- Publisher copy:
- 10.1073/pnas.1802893115
-
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- Grant:
- MSP131411 and KENN151611 (to G.L., A.I.E.S., M.F., N.J.H., and J.N.)
- Publisher:
- National Academy of Sciences Publisher's website
- Journal:
- Proceedings of the National Academy of Sciences Journal website
- Volume:
- 115
- Issue:
- 19
- Pages:
- E4463-E4472
- Publication date:
- 2018-04-19
- Acceptance date:
- 2018-04-06
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Pubs id:
-
pubs:840493
- URN:
-
uri:6cd07b87-2994-4a83-801e-08243c46d6a6
- UUID:
-
uuid:6cd07b87-2994-4a83-801e-08243c46d6a6
- Local pid:
- pubs:840493
- Keywords:
- Copyright holder:
- Lee et al.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 the Authors. Published by PNAS.
This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).
Journal article
Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to GAlert
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