A major discovery of recent decades has been the existence of stem cells and their potential to repair many, if not most, tissues. With the aging population, many attempts have been made to use exogenous stem cells to promote tissue repair, so far with limited success. An alternative approach, which may be more effective and far less costly, is to promote tissue regeneration by targeting endogenous stem cells. However, ways of enhancing endogenous stem cell function remain poorly defined. Inj...Expand abstract
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Copyright © 2018 the Authors. Published by PNAS.
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Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to GAlert
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