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Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma.

Abstract:

Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sputum eosinophilia, but in contrast to asthma there is no variable airflow obstruction or airway hyperresponsiveness. Our hypothesis was that the differences in airway pathophysiology maybe due to less active airway inflammation in eosinophilic bronchitis, with reduced release of important effector mediators. We measured the concentration of various proinflammatory mediators in induced sputum ce...

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Authors


Brightling, CE More by this author
Woltmann, G More by this author
Bradding, P More by this author
Sheller, JR More by this author
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Journal:
American journal of respiratory and critical care medicine
Volume:
162
Issue:
3 Pt 1
Pages:
878-882
Publication date:
2000-09-05
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:6cc44192-1299-41f2-a9cb-3ec2b1ecb03d
Source identifiers:
435367
Local pid:
pubs:435367

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