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A multi-site, multi-disorder resting-state magnetic resonance image database

Abstract:

Machine learning classifiers for psychiatric disorders using resting-state functional magnetic resonance imaging (rs-fMRI) have recently attracted attention as a method for directly examining relationships between neural circuits and psychiatric disorders. To develop accurate and generalizable classifiers, we compiled a large-scale, multi-site, multi-disorder neuroimaging database. The database comprises resting-state fMRI and structural images of the brain from 993 patients and 1,421 healthy individuals, as well as demographic information such as age, sex, and clinical rating scales. To harmonize the multi-site data, nine healthy participants (“traveling subjects”) visited the sites from which the above datasets were obtained and underwent neuroimaging with 12 scanners. All participants consented to having their data shared and analyzed at multiple medical and research institutions participating in the project, and 706 patients and 1,122 healthy individuals consented to having their data disclosed. Finally, we have published four datasets: 1) the SRPBS Multi-disorder Connectivity Dataset 2), the SRPBS Multi-disorder MRI Dataset (restricted), 3) the SRPBS Multi-disorder MRI Dataset (unrestricted), and 4) the SRPBS Traveling Subject MRI Dataset.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41597-021-01004-8

Authors


More by this author
Role:
Author
ORCID:
0000-0002-7001-5051
More by this author
Role:
Author
ORCID:
0000-0003-3825-2919
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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-9273-1617
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0003-1724-5832
et al.


Publisher:
Springer Nature
Journal:
Scientific Data More from this journal
Volume:
8
Issue:
1
Article number:
227
Publication date:
2021-08-30
Acceptance date:
2021-07-26
DOI:
EISSN:
2052-4463
Pmid:
34462444


Language:
English
Keywords:
Pubs id:
1193703
Local pid:
pubs:1193703
Deposit date:
2023-02-28

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