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Conservation and variability of dengue virus proteins: implications for vaccine design

Abstract:

Article Authors Metrics Comments Media Coverage Abstract Author Summary Introduction Methods Results Discussion Supporting Information Acknowledgments Author Contributions References Reader Comments (0) Media Coverage (0) Figures Abstract Background Genetic variation and rapid evolution are hallmarks of RNA viruses, the result of high mutation rates in RNA replication and selection of mutants that enhance viral adaptation, including the escape from host immune responses. Variability is uneven...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pntd.0000272

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Publisher:
Public Library of Science
Journal:
PLoS Neglected Tropical Diseases More from this journal
Volume:
2
Issue:
8
Pages:
ARTN e272
Publication date:
2008-08-13
Acceptance date:
2008-07-10
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Language:
English
Keywords:
UUID:
uuid:6ca8f120-1902-40f6-964f-929b6f43992d
Local pid:
pubs:34349
Source identifiers:
34349
Deposit date:
2012-12-19

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