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The structure of linkage disequilibrium around a selective sweep.

Abstract:

The fixation of advantageous mutations by natural selection has a profound impact on patterns of linked neutral variation. While it has long been appreciated that such selective sweeps influence the frequency spectrum of nearby polymorphism, it has only recently become clear that they also have dramatic effects on local linkage disequilibrium. By extending previous results on the relationship between genealogical structure and linkage disequilibrium, I obtain simple expressions for the influe...

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Publication status:
Published

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Publisher copy:
10.1534/genetics.106.062828

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Journal:
Genetics More from this journal
Volume:
175
Issue:
3
Pages:
1395-1406
Publication date:
2007-03-01
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
Language:
English
Keywords:
Pubs id:
pubs:103161
UUID:
uuid:6c49d970-1464-4e13-bf4b-23d28aa82cf3
Local pid:
pubs:103161
Source identifiers:
103161
Deposit date:
2012-12-19

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