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Journal article

Nanoparticles can wrap epithelial cell membranes and relocate them across the epithelial cell layer

Abstract:

Although the link between the inhalation of nanoparticles and cardiovascular disease is well established, the causal pathway between nanoparticle exposure and increased activity of blood coagulation factors remains unexplained. To initiate coagulation tissue factor bearing epithelial cell membranes should be exposed to blood, on the other side of the less than a micrometre thin air-blood barrier. For the inhaled nanoparticles to promote coagulation, they need to bind lung epithelial-cell memb...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1021/acs.nanolett.8b02291

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM - Investigative Medicine Division
Majaron, H More by this author
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Slovenian Research Agency More from this funder
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Publisher:
American Chemical Society Publisher's website
Journal:
Nano Letters Journal website
Volume:
18
Issue:
8
Pages:
5294-5305
Publication date:
2018-07-24
Acceptance date:
2018-07-24
DOI:
EISSN:
1530-6992
ISSN:
1530-6984
Pubs id:
pubs:891323
URN:
uri:6c0cd661-1736-4b2d-899d-b656b67c26c0
UUID:
uuid:6c0cd661-1736-4b2d-899d-b656b67c26c0
Local pid:
pubs:891323

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