Journal article
The Warburg Effect: 80 years on
- Abstract:
-
Influential research by Warburg and Cori in the 1920’s ignited interest in how cancer cells’ energy generation is different to normal cells’. They observed high glucose consumption and large amounts of lactate excretion from cancer cells compared to normal cells which oxidised glucose using mitochondria. It was therefore assumed that cancer cells were generating energy using glycolysis rather than mitochondrial oxidative phosphorylation and that the mitochondria were dysfunctional. Advances i...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Portland Press Publisher's website
- Journal:
- Biochemical Society Transactions Journal website
- Volume:
- 44
- Issue:
- 5
- Pages:
- 1499-1505
- Publication date:
- 2016-10-01
- Acceptance date:
- 2016-07-26
- DOI:
Item Description
- Keywords:
- Pubs id:
-
pubs:635411
- UUID:
-
uuid:6bfc1260-b23a-43a7-b650-b62172935dd5
- Local pid:
- pubs:635411
- Source identifiers:
-
635411
- Deposit date:
- 2016-07-26
Terms of use
- Copyright holder:
- Morten et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND).
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