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Enzymatic kinetic resolution by addition of oxygen

Abstract:

Kinetic resolution using biocatalysis has proven to be an excellent complementary technique to traditional asymmetric catalysis for the production of enantioenriched compounds. Resolution using oxidative enzymes produces valuable oxygenated structures for use in synthetic route development. This Minireview focuses on enzymes which catalyse the insertion of an oxygen atom into the substrate and, in so doing, can achieve oxidative kinetic resolution. The Baeyer–Villiger rearrangement, epoxidati...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/anie.202011468

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Author
ORCID:
0000-0003-4875-1092
More by this author
Institution:
University of Oxford
Role:
Author
Publisher:
Wiley
Journal:
Angewandte Chemie International Edition More from this journal
Volume:
60
Issue:
9
Pages:
4434-4447
Publication date:
2020-10-10
Acceptance date:
2020-10-08
DOI:
EISSN:
1521-3773
ISSN:
1433-7851
Language:
English
Keywords:
Pubs id:
1137410
Local pid:
pubs:1137410
Deposit date:
2020-10-13

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