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Journal article : Review

Studying the endothelial glycocalyx in vitro: what is missing?

Abstract:

All human cells are coated by a surface layer of proteoglycans, glycosaminoglycans (GAGs) and plasma proteins, called the glycocalyx. The glycocalyx transmits shear stress to the cytoskeleton of endothelial cells, maintains a selective permeability barrier, and modulates adhesion of blood leukocytes and platelets. Major components of the glycocalyx, including syndecans, heparan sulfate, and hyaluronan, are shed from the endothelial surface layer during conditions including ischaemia and hypox...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3389/fcvm.2021.647086

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Publisher:
Frontiers Media
Journal:
Frontiers in Cardiovascular Medicine More from this journal
Volume:
8
Article number:
647086
Publication date:
2021-04-14
Acceptance date:
2021-03-19
DOI:
EISSN:
2297-055X
Pmid:
33937360
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1175778
Local pid:
pubs:1175778
Deposit date:
2021-07-16

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