Mitigating the threat of artemisinin resistance in Africa: improvement of drug-resistance surveillance and response systems.

Journal article

Artemisinin-resistant Plasmodium falciparum malaria has emerged in western Cambodia and has been detected in western Thailand. The situation is ominously reminiscent of the emergence of resistance to chloroquine and to sulfadoxine-pyrimethamine several decades ago. Artemisinin resistance is a major threat to global public health, with the most severe potential effects in sub-Saharan Africa, where the disease burden is highest and systems for monitoring and containment of resistance are inadeq...

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Authors: Talisuna, A; Karema, C; Ogutu, B; Juma, E; Logedi, J

• Publication status: Published
• Journal: Lancet. Infectious diseases
• Volume: 12
• Issue: 11
• Pages: 888-896
• Publication date: 2012-11-01
• DOI: 10.1016/S1473-3099(12)70241-4
• EISSN: 1474-4457
• ISSN: 1473-3099
• Language: English
• Keywords: Africa South of the Sahara; Communicable Disease Control; Plasmodium falciparum; Malaria, Falciparum; Artemisinins; Humans; World Health Organization; Antimalarials; Drug Resistance; Africa; Sentinel Surveillance