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Improved electrotransformation and decreased antibiotic resistance of the cystic fibrosis pathogen Burkholderia cenocepacia strain J2315.

Abstract:

The bacterium Burkholderia cenocepacia is pathogenic for sufferers from cystic fibrosis (CF) and certain immunocompromised conditions. The B. cenocepacia strain most frequently isolated from CF patients, and which serves as the reference for CF epidemiology, is J2315. The J2315 genome is split into three chromosomes and one plasmid. The strain was sequenced several years ago, and its annotation has been released recently. This information should allow genetic experimentation with J2315, but t...

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Publication status:
Published

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Publisher copy:
10.1128/aem.02123-09

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Applied and environmental microbiology
Volume:
76
Issue:
4
Pages:
1095-1102
Publication date:
2010-02-05
DOI:
EISSN:
1098-5336
ISSN:
0099-2240
URN:
uuid:6b5a31c8-bf51-4ec8-af65-d039edc9d1b5
Source identifiers:
55392
Local pid:
pubs:55392

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