Journal article icon

Journal article : Review

The application of single-cell RNA sequencing in vaccinology

Abstract:

Single-cell RNA sequencing allows highly detailed profiling of cellular immune responses from limited-volume samples, advancing prospects of a new era of systems immunology. The power of single-cell RNA sequencing offers various opportunities to decipher the immune response to infectious diseases and vaccines. Here, we describe the potential uses of single-cell RNA sequencing methods in prophylactic vaccine development, concentrating on infectious diseases including COVID-19. Using examples f...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1155/2020/8624963

Authors


More by this author
Role:
Author
ORCID:
0000-0002-6408-7032
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0002-0860-0831
More from this funder
Name:
National Institute for Health Research
Grant:
NF-SI-0617-10139
Publisher:
Hindawi
Journal:
Journal of Immunology Research More from this journal
Volume:
2020
Article number:
8624963
Publication date:
2020-08-06
Acceptance date:
2020-07-09
DOI:
EISSN:
2314-7156
ISSN:
2314-8861
Pmid:
32802896
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1127906
Local pid:
pubs:1127906
Deposit date:
2020-08-26

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP