Journal article
Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways
- Abstract:
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Background Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by “bulk” assays and to uncover rare cell types. In human hematopoiesis, megakaryocytes and erythroid cells differentiate from a shared precursor, the megakaryocyte-erythroid progenitor (MEP), which remains poorly defined. Results To clarify the cellular pathway in erythro-megakaryocyte differentiat... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.9MB)
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- Publisher copy:
- 10.1186/s13059-016-0939-7
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Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Genome Biology Journal website
- Volume:
- 17
- Issue:
- 1
- Article number:
- 83
- Publication date:
- 2016-05-01
- Acceptance date:
- 2016-04-08
- DOI:
- EISSN:
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1474-760X
- ISSN:
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1465-6906
- Source identifiers:
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614779
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:614779
- UUID:
-
uuid:6add9a33-1ce0-4bfb-9469-e429ba88f3bc
- Local pid:
- pubs:614779
- Deposit date:
- 2016-05-19
Terms of use
- Copyright holder:
- Psaila et al
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Psaila et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
- Licence:
- CC Attribution (CC BY)
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