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Mapping the epigenetic modifications of DNA and RNA

Abstract:

Over 17 and 160 types of chemical modifications have been identified in DNA and RNA, respectively. The interest in understanding the various biological functions of DNA and RNA modifications has lead to the cutting-edged fields of epigenomics and epitranscriptomics. Developing chemical and biological tools to detect specific modifications in the genome or transcriptome has greatly facilitated their study. Here, we review the recent technological advances in this rapidly evolving field. We foc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s13238-020-00733-7

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
ORCID:
0000-0003-3451-0212
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
ORCID:
0000-0003-0096-4187
Emerson Collective More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
Protein and Cell Journal website
Volume:
11
Issue:
11
Pages:
792–808
Publication date:
2020-05-22
Acceptance date:
2020-03-16
DOI:
EISSN:
1674-8018
ISSN:
1674-800X
Language:
English
Keywords:
Pubs id:
1095201
Local pid:
pubs:1095201
Deposit date:
2020-03-19

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