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Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies: therapeutics based on molecular phenotype.

Abstract:: The enduring subdivision of cardiomyopathies into hypertrophic (HCM), dilated (DCM), and restrictive (RCM) categories reflects the emphasis of traditional classifications on morphology. Rapid advances in the genetic interrogation of these disorders have redefined their taxonomy and revealed potential conflicts between the old and new classifications. Hypertrophic cardiomyopathy has been redefined as a disease of perturbed sarcomere function. Dilated cardiomyopathy is a disease that results fr...
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Publication status:: Published

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APA Style

Ashrafian, H., & Watkins, H. (2007). Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies: therapeutics based on molecular phenotype. Journal of the American College of Cardiology, 49(12), 1251–1264.

MLA Style

Ashrafian, H., and H. Watkins. “Reviews of Translational Medicine and Genomics in Cardiovascular Disease: New Disease Taxonomy and Therapeutic Implications Cardiomyopathies: Therapeutics Based on Molecular Phenotype.” Journal of the American College of Cardiology, vol. 49, no. 12, 2007, pp. 1251–64.

Chicago Style

Ashrafian, H, and H Watkins. 2007. “Reviews of Translational Medicine and Genomics in Cardiovascular Disease: New Disease Taxonomy and Therapeutic Implications Cardiomyopathies: Therapeutics Based on Molecular Phenotype.” Journal of the American College of Cardiology 49 (12): 1251–64.
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Publisher copy:: 10.1016/j.jacc.2006.10.073

Authors

+ Ashrafian, H More by this author

Institution:

University of Oxford

Division:

MSD

Department:

RDM

Sub department:

RDM Cardiovascular Medicine

Role:

Author

+ Watkins, H More by this author

Role:

Author

Bibliographic Details

Journal:: Journal of the American College of Cardiology
Volume:: 49
Issue:: 12
Pages:: 1251-1264
Publication date:: 2007-03-01
DOI:: 10.1016/j.jacc.2006.10.073
EISSN:: 1558-3597
ISSN:: 0735-1097

Item Description

Language:: English
Keywords:: Humans

Genomics

Genetic Testing

Cardiovascular Diseases

Cardiomyopathies

Phenotype
Pubs id:: pubs:104232
UUID:: uuid:6a8d85d8-5207-4171-ac36-1d51e1d9add5
Local pid:: pubs:104232
Source identifiers:: 104232
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2007

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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