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Journal article

Memory and the lifespan of human T lymphocytes.

Abstract:

The properties of human CD45RA and CD45R0 T cells are described. CD45R0 cells respond to recall antigens and provide help for B lymphocytes. They produce a wide variety of cytokines including IL-2, IL-4 and IFN-gamma. CD45RA T cells respond poorly to recall antigens and produce mainly IL-2. The phenotype of CD45R0 cells suggests that they may be in cycle and in vivo data shows that they have a short lifespan while CD45RA cells are long lived. The lineage relationship of the two subsets is not...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Leukemia
Volume:
7 Suppl 2
Issue:
SUPPL. 2
Pages:
S50-S54
Publication date:
1993-08-01
EISSN:
1476-5551
ISSN:
0887-6924
Source identifiers:
35845
Language:
English
Keywords:
Pubs id:
pubs:35845
UUID:
uuid:6a894524-d3e7-49a4-b4ac-b83c96069815
Local pid:
pubs:35845
Deposit date:
2012-12-20

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