Journal article icon

Journal article

Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom

Abstract:

We report that in a cohort of 45,965 adults, who were receiving either the ChAdOx1 or the BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2, seroconversion rates and quantitative antibody levels after a single dose were lower in older individuals, especially in those aged >60 years. Two vaccine doses achieved high responses across all ages. Antibody levels increased more slowly and to lower levels with a single dose of ChAdOx1 compared with a single dose of BNT...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/s41564-021-00947-3

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Green Templeton College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Publisher:
Springer Nature
Journal:
Nature Microbiology More from this journal
Volume:
6
Issue:
2021
Pages:
1140–1149
Publication date:
2021-07-21
Acceptance date:
2021-07-01
DOI:
EISSN:
2058-5276
Language:
English
Keywords:
Pubs id:
1186196
Local pid:
pubs:1186196
Deposit date:
2021-07-13

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP