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The location of binding sites of pemphigus vulgaris and pemphigus foliaceus autoantibodies: a post-embedding immunoelectron microscopic study.

Abstract:

Pemphigus is a life-threatening autoimmune blistering disease of skin and mucous membranes that has two major subtypes based on clinical and histological features, pemphigus vulgaris (PV) and pemphigus foliaceus (PF). Autoantibodies against the PV antigen (desmoglein 3) and the PF antigen (desmoglein 1) are involved in the pathogenesis of blister formation. In the present study, the location of epitopes recognized by autoantibodies of patients with PV and PF was studied by postembedding immun...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
The British journal of dermatology
Volume:
136
Issue:
6
Pages:
878-883
Publication date:
1997-06-05
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
URN:
uuid:6a4a8911-8cd4-42c6-8eb1-df775f43b8cc
Source identifiers:
10567
Local pid:
pubs:10567

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