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Hemochromatosis (HFE) gene mutations and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

Abstract:

Hereditary hemochromatosis (HH) is a strong risk factor for hepatocellular cancer, and mutations in the HFE gene associated with HH and iron overload may be related to other tumors, but no studies have been reported for gastric cancer (GC). A nested case-control study was conducted within the European Prospective Investigation into Cancer and Nutrition (EPIC), including 365 incident gastric adenocarcinoma and 1284 controls matched by center, sex, age and date of blood collection. Genotype ana...

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Publication status:
Published

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Publisher copy:
10.1093/carcin/bgt045

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Journal:
Carcinogenesis
Volume:
34
Issue:
6
Pages:
1244-1250
Publication date:
2013-06-05
DOI:
EISSN:
1460-2180
ISSN:
0143-3334
URN:
uuid:6a2f3e82-ad87-4313-a26d-aeab4a535f80
Source identifiers:
410028
Local pid:
pubs:410028

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