Journal article icon

Journal article

Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions.

Abstract:

Research in the past two decades has generated unequivocal evidence that host genetic variations substantially account for the heterogeneous outcomes following human immunodeficiency virus type 1 (HIV-1) infection. In particular, genes encoding human leukocyte antigens (HLA) have various alleles, haplotypes, or specific motifs that can dictate the set-point (a relatively steady state) of plasma viral load (VL), although rapid viral evolution driven by innate and acquired immune responses can ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s00439-014-1465-x

Authors


Expand authors...
Journal:
Human genetics
Volume:
133
Issue:
9
Pages:
1187-1197
Publication date:
2014-09-05
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
URN:
uuid:6a1012d6-4fee-45d1-a064-c4a5c11797ba
Source identifiers:
474104
Local pid:
pubs:474104

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP