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Teratogen update: maternal myasthenia gravis as a cause of congenital arthrogryposis.

Abstract:

BACKGROUND: Arthrogryposis multiplex congenita (AMC) is defined as nonprogressive congenital contractures that generally result from lack of fetal movement in utero. AMC is a feature of many congenital disorders caused by genetic, environmental, or other factors. One rare cause of AMC is maternal myasthenia gravis (MG). This is an autoimmune disorder, caused by antibodies to the nicotinic acetylcholine receptor (AChR), and resulting in weakness of voluntary muscles. In 10-15% of babies born t...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Teratology More from this journal
Volume:
62
Issue:
5
Pages:
332-341
Publication date:
2000-11-01
DOI:
ISSN:
0040-3709
Language:
English
Keywords:
Pubs id:
pubs:242110
UUID:
uuid:69ee72ba-3696-4f8b-a9a1-f62b33891cb5
Local pid:
pubs:242110
Source identifiers:
242110
Deposit date:
2012-12-19

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