Journal article icon

Journal article

Chromosome-wide analysis of gene function by RNA interference in the african trypanosome.

Abstract:

Trypanosomatids of the order Kinetoplastida are major contributors to global disease and morbidity, and understanding their basic biology coupled with the development of new drug targets represents a critical need. Additionally, trypanosomes are among the more accessible divergent eukaryote experimental systems. The genome of Trypanosoma brucei contains 8,131 predicted open reading frames (ORFs), of which over half have no known homologues beyond the Kinetoplastida and a substantial number of...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1128/ec.00141-06

Authors


Journal:
Eukaryotic cell
Volume:
5
Issue:
9
Pages:
1539-1549
Publication date:
2006-09-01
DOI:
EISSN:
1535-9786
ISSN:
1535-9778
Language:
English
Keywords:
Pubs id:
pubs:20645
UUID:
uuid:69e69f3e-3b36-4601-8e1c-21527f15dbee
Local pid:
pubs:20645
Source identifiers:
20645
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP