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Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray.

Abstract:

Diffuse large B-cell lymphoma (DLBCL) can be divided into prognostically important subgroups with germinal center B-cell-like (GCB), activated B-cell-like (ABC), and type 3 gene expression profiles using a cDNA microarray. Tissue microarray (TMA) blocks were created from 152 cases of DLBCL, 142 of which had been successfully evaluated by cDNA microarray (75 GCB, 41 ABC, and 26 type 3). Sections were stained with antibodies to CD10, bcl-6, MUM1, FOXP1, cyclin D2, and bcl-2. Expression of bcl-6...

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Publication status:
Published

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Publisher copy:
10.1182/blood-2003-05-1545

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Journal:
Blood
Volume:
103
Issue:
1
Pages:
275-282
Publication date:
2004-01-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:69a62161-7141-49b0-8d74-d9b84cc11850
Source identifiers:
246703
Local pid:
pubs:246703

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