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Interferon lambdas: The next cytokine storm

Abstract:

For two decades the scientific community has sought to understand why some people clear hepatitis C virus (HCV) and others do not. Recently, several large genome-wide association studies have identified single nucleotide polymorphisms (SNPs) linked to interferon lambda 3 (IFNλ3) that are associated with the spontaneous resolution and successful treatment of HCV infection. These observations are generating intense research activity; the hope is that IFNλ3 genetic variants may serve as importan...

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Publisher copy:
10.1136/gut.2010.222976

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Gut
Volume:
60
Issue:
9
Pages:
1284-1293
Publication date:
2011-09-01
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
Source identifiers:
179315
Language:
English
Pubs id:
pubs:179315
UUID:
uuid:698150b5-c5d6-4482-a275-fb9583480ef7
Local pid:
pubs:179315
Deposit date:
2012-12-19

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