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Journal article

P450(BM3) on steroids: the Swiss Army knife P450 enzyme just gets better.

Abstract:
The catalytic regio- and stereoselective oxidation of aliphatic C-H bonds by using atmospheric dioxygen as the oxidant is a highly desirable reaction. Reetz and co-workers have recently reported the development of P450(BM3) mutants that oxidise testosterone with greatly increased turnover activity, total stereoselectivity and >95 % regioselectivity.
Publication status:
Published

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Publisher copy:
10.1002/cbic.201100606

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
Journal:
Chembiochem : a European journal of chemical biology More from this journal
Volume:
12
Issue:
17
Pages:
2537-2539
Publication date:
2011-11-01
DOI:
EISSN:
1439-7633
ISSN:
1439-4227
Language:
English
Keywords:
Pubs id:
pubs:193380
UUID:
uuid:68b8aef3-7550-4272-b6ec-fc38d8181881
Local pid:
pubs:193380
Source identifiers:
193380
Deposit date:
2012-12-19

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