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Journal article

Osteoclast-like cells in soft tissue leiomyosarcomas.

Abstract:

Giant cell-rich leiomyosarcoma of soft tissues is an unusual variant of malignant smooth muscle tumor characterized by the presence of numerous multinucleated giant cells (MNGCs). The nature of MNGCs and the cellular mechanisms underlying their accumulation in this tumor are poorly understood. Analysis of the expression of osteoclast, macrophage, and smooth muscle markers in two cases of giant cell-rich leiomyosarcoma revealed that the MNGCs in giant cell-rich leiomyosarcoma were negative for...

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Publication status:
Published

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Publisher copy:
10.1007/s00428-010-0882-z

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Journal:
Virchows Archiv : an international journal of pathology
Volume:
456
Issue:
3
Pages:
317-323
Publication date:
2010-03-05
DOI:
EISSN:
1432-2307
ISSN:
0945-6317
URN:
uuid:6893b7d2-64df-4037-a80e-4974730187b8
Source identifiers:
103898
Local pid:
pubs:103898

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