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Journal article

ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice

Abstract:

The Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more than 1900 humans, since 2012. The syndrome ranges from asymptomatic and mild cases to severe pneumonia and death. The virus is believed to be circulating in dromedary camels without notable symptoms since the 1980s. Therefore, dromedary camels are considered the only animal source of infection. Neither antiviral drugs nor vaccines are approved for veterinary or medical use despite active research on this area. Here,...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.vaccine.2017.05.032

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
35
Issue:
30
Pages:
3780-3788
Publication date:
2017-06-01
Acceptance date:
2017-05-10
DOI:
ISSN:
0264-410X
Source identifiers:
697733
Pubs id:
pubs:697733
UUID:
uuid:6874f729-41df-4276-b25d-8edada2bffee
Local pid:
pubs:697733
Deposit date:
2017-05-31

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