Journal article
Neuro-mesenchymal units control ILC2 and obesity via a brain–adipose circuit
- Abstract:
-
Signals from sympathetic neurons and immune cells regulate adipocytes and thereby contribute to fat tissue biology. Interactions between the nervous and immune systems have recently emerged as important regulators of host defence and inflammation1,2,3,4. Nevertheless, it is unclear whether neuronal and immune cells co-operate in brain–body axes to orchestrate metabolism and obesity. Here we describe a neuro-mesenchymal unit that controls group 2 innate lymphoid cells (ILC2s), adipose tissue p...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Journal website
- Volume:
- 597
- Pages:
- 410-414
- Publication date:
- 2021-08-18
- Acceptance date:
- 2021-07-16
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1192769
- Local pid:
- pubs:1192769
- Deposit date:
- 2021-08-26
Terms of use
- Copyright holder:
- Cardoso et al.
- Copyright date:
- 2021
- Rights statement:
- Copyright © 2021, The Author(s), under exclusive licence to Springer Nature Limited
- Notes:
-
This is the accepted manuscript version of the article. The final version is available from Springer Nature at https://doi.org/10.1038/s41586-021-03830-7
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