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Mesenchymal cells expressing bone morphogenetic protein receptors are present in the rheumatoid arthritis joint.

Abstract:

OBJECTIVE: To evaluate the presence of cells of an early mesenchymal lineage, as judged by the expression of bone morphogenetic protein receptors (BMPRs), in the joints of normal individuals and patients with rheumatoid arthritis (RA). METHODS: Synovial fluids, single cell suspensions of cultured fibroblast-like synoviocytes (FLS), and synovial tissues were examined by immunohistology with antibodies to BMPR type IA (BMPRIA), BMPRIB, and BMPRII and then quantified using computerized image ana...

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Journal:
Arthritis and rheumatism More from this journal
Volume:
43
Issue:
9
Pages:
2046-2055
Publication date:
2000-09-01
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
Language:
English
Keywords:
Pubs id:
pubs:377338
UUID:
uuid:68601b89-e621-43c2-9d9a-7a661986abd1
Local pid:
pubs:377338
Source identifiers:
377338
Deposit date:
2013-11-16

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