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Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial.

Abstract:

WHO 2013 guidelines recommend universal treatment for HIV-infected children younger than 5 years. No paediatric trials have compared nucleoside reverse-transcriptase inhibitors (NRTIs) in first-line antiretroviral therapy (ART) in Africa, where most HIV-infected children live. We aimed to compare stavudine, zidovudine, or abacavir as dual or triple fixed-dose-combination paediatric tablets with lamivudine and nevirapine or efavirenz.In this open-label, parallel-group, randomised trial (CHAPAS...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/S1473-3099(15)00319-9

Authors


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Medical Research Council More from this funder
Department for International Development More from this funder
Ministerio de Sanidady Consumo Spain More from this funder
Publisher:
Elsevier Publisher's website
Journal:
The Lancet. Infectious diseases Journal website
Volume:
16
Issue:
2
Pages:
169-179
Publication date:
2016-02-05
DOI:
EISSN:
1474-4457
ISSN:
1473-3099
URN:
uuid:6812cf0e-1a17-4f31-8427-186c0e240f35
Source identifiers:
588407
Local pid:
pubs:588407
Language:
English
Keywords:

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