Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsy.
BACKGROUND: In women younger than 45 years, a new form of encephalitis associated with ovarian teratoma and presenting with seizures and psychiatric symptoms has been described. Most patients have antibodies to NR1/NR2 heteromers of the N-methyl-D-aspartate receptor (NMDAR). OBJECTIVE: To assess the frequency and significance of antibodies to NMDAR in otherwise unexplained new-onset epilepsies in young women. DESIGN: Prospective cohort study. SETTING: University department of epileptology. P...Expand abstract
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