Journal article
Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases.
- Abstract:
-
Tissue inflammation results in the production of numerous reactive oxygen, nitrogen and chlorine species, in addition to the products of lipid and sugar oxidation. Some of these products are capable of chemically modifying amino acids. This in turn results in changes to the structure and function of proteins. Increasing evidence demonstrates that such oxidative post-translational modifications result in the generation of neo-epitopes capable of eliciting both innate and adaptive immune respon...
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Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Redox biology
- Volume:
- 2
- Issue:
- 1
- Pages:
- 715-724
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
2213-2317
- ISSN:
-
2213-2317
Item Description
- Language:
- English
- Pubs id:
-
pubs:471714
- UUID:
-
uuid:67073d94-4755-475f-b8e3-2943c7da88e4
- Local pid:
- pubs:471714
- Source identifiers:
-
471714
- Deposit date:
- 2014-10-31
Terms of use
- Copyright date:
- 2014
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