Journal article
Abcc5 knockout mice have lower fat mass and increased levels of circulating GLP‐1
- Abstract:
-
Objective A previous genome‐wide association study linked overexpression of an ATP‐binding cassette transporter, ABCC5, in humans with a susceptibility to developing type 2 diabetes with age. Specifically, ABCC5 gene overexpression was shown to be strongly associated with increased visceral fat mass and reduced peripheral insulin sensitivity. Currently, the role of ABCC5 in diabetes and obesity is unknown. This study reports the metabolic phenotyping of a global Abcc5 knockou... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Cyranka, M
Grant:
BB/P020666/1
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Obesity Journal website
- Volume:
- 27
- Issue:
- 8
- Pages:
- 1292-1304
- Publication date:
- 2019-07-24
- Acceptance date:
- 2019-04-09
- DOI:
- EISSN:
-
1930-739X
- ISSN:
-
1930-7381
- Pmid:
-
31338999
- Source identifiers:
-
1036789
Item Description
- Language:
- English
- Pubs id:
-
pubs:1036789
- UUID:
-
uuid:66a660c8-b712-4a61-afb9-64ba64aa795f
- Local pid:
- pubs:1036789
- Deposit date:
- 2019-08-02
Terms of use
- Copyright holder:
- Cyranka et al
- Copyright date:
- 2019
- Notes:
- © 2019 The Authors Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS). This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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