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Thesis

The eukaryotic flagellum in health and disease

Abstract:

The 9 + 2 microtubule axoneme of flagella and cilia represents one of the most iconic structures built by eukaryotic cells and organisms. Some cilia are motile, whilst others serve as sensory organelles, and can variously possess 9+2, 9+0 axonemes and other associated structures. The recent emergence of ciliary dysfunction as a cause of human disease has renewed interest in these organelles, with several genomic and proteomic studies of cilia and flagella now published from various systems...

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Peer Reviewed

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Department:
University of Oxford
This thesis was digitised thanks to the generosity of Dr Leonard Polonsky More from this funder
Publication date:
2007
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Local pid:
polonsky:2:51

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