Thesis
Synthesis of deuterated phosphatidylinositol phosphates
- Abstract:
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Phosphatidylinositol phosphates (PtdInsPn) are intracellular signalling molecules that are important in many key biological processes, in particular Ca2+ signalling pathways. Dysfunction of these processes has been implicated in numerous diseases including diabetes and many cancers. Some aspects of PtdInsPn signalling have been heavily investigated; PTEN, PKC/Akt, PtdIns3K and PtdIns4K are all important therapeutic targets that have seen much attention in i...
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Authors
Contributors
+ Conway, S
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Supervisor
+ Sanganee, H
Department:
AstraZeneca
Role:
Supervisor
+ Smith, M
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Examiner
+ Lewis, S
Department:
University of Bath
Role:
Examiner
Funding
+ Engineering & Physical Sciences Research Council
More from this funder
Funding agency for:
Saunders, A
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:65f93fcc-791a-491f-88c5-8ccb5db58592
- Deposit date:
- 2017-01-31
Terms of use
- Copyright holder:
- Saunders, A
- Copyright date:
- 2016
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