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Thesis

Synthesis of deuterated phosphatidylinositol phosphates

Abstract:

Phosphatidylinositol phosphates (PtdInsPn) are intracellular signalling molecules that are important in many key biological processes, in particular Ca2+ signalling pathways. Dysfunction of these processes has been implicated in numerous diseases including diabetes and many cancers. Some aspects of PtdInsPn signalling have been heavily investigated; PTEN, PKC/Akt, PtdIns3K and PtdIns4K are all important therapeutic targets that have seen much attention in i...

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Institution:
University of Oxford
Division:
MPLS
Department:
Doctoral Training Centre - MPLS
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Supervisor
Department:
AstraZeneca
Role:
Supervisor
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Examiner
Department:
University of Bath
Role:
Examiner
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Funding agency for:
Saunders, A
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:65f93fcc-791a-491f-88c5-8ccb5db58592
Deposit date:
2017-01-31

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