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Insulin signalling through ultradian oscillations.

Abstract:

Periodic oscillations appear to be a characteristic of insulin secretion at various different levels. Very rapid pulsations are seen in the isolated beta-cell and islet, while rapid (10- to 15-min) pulsations are seen both in the intact organism and in the isolated pancreas. Ultradian oscillations, particularly evident in situations of sustained exogenous glucose loading, appear to be a characteristic of intact organisms and have been hypothesized to be intrinsic to the normal glucose-insulin...

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Growth hormone and IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Volume:
11 Suppl A
Issue:
SUPPL. 1
Pages:
S17-S23
Publication date:
2001-06-01
DOI:
EISSN:
1532-2238
ISSN:
1096-6374
Source identifiers:
31934
Language:
English
Keywords:
Pubs id:
pubs:31934
UUID:
uuid:65f7fc54-b92f-447e-a61d-f58adaefe23e
Local pid:
pubs:31934
Deposit date:
2012-12-19

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