Journal article : Review
Fibroblasts as immune regulators in infection, inflammation and cancer
- Abstract:
-
In chronic infection, inflammation and cancer, the tissue microenvironment controls how local immune cells behave, with tissue-resident fibroblasts emerging as a key cell type in regulating activation or suppression of an immune response. Fibroblasts are heterogeneous cells, encompassing functionally distinct populations, the phenotypes of which differ according to their tissue of origin and type of inciting disease. Their immunological properties are also diverse, ranging from the maintenanc...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Reviews Immunology Journal website
- Volume:
- 21
- Issue:
- 11
- Pages:
- 704–717
- Publication date:
- 2021-04-28
- Acceptance date:
- 2021-03-11
- DOI:
- EISSN:
-
1474-1741
- ISSN:
-
1474-1733
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
1159021
- Local pid:
- pubs:1159021
- Deposit date:
- 2021-01-28
Terms of use
- Copyright holder:
- Springer Nature Limited
- Copyright date:
- 2021
- Rights statement:
- © Springer Nature Limited 2021.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/s41577-021-00540-z
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