Journal article
Selective chemical protein modification.
- Abstract:
-
Chemical modification of proteins is an important tool for probing natural systems, creating therapeutic conjugates and generating novel protein constructs. Site-selective reactions require exquisite control over both chemo- and regioselectivity, under ambient, aqueous conditions. There are now various methods for achieving selective modification of both natural and unnatural amino acids--each with merits and limitations--providing a 'toolkit' that until 20 years ago was largely limited to re...
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Bibliographic Details
- Journal:
- Nature communications
- Volume:
- 5
- Pages:
- 4740
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
2041-1723
Item Description
- Language:
- English
- Pubs id:
-
pubs:484061
- UUID:
-
uuid:65979bb6-a9be-472b-b4ba-868de5c67b53
- Local pid:
- pubs:484061
- Source identifiers:
-
484061
- Deposit date:
- 2014-09-17
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- Copyright date:
- 2014
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