Journal article
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
- Abstract:
-
OBJECTIVE:To identify a plasma metabolomic biomarker signature for migraine. METHODS:Plasma samples from 8 Dutch cohorts (n = 10,153: 2,800 migraine patients and 7,353 controls) were profiled on a 1H-NMR-based metabolomics platform, to quantify 146 individual metabolites (e.g., lipids, fatty acids, and lipoproteins) and 79 metabolite ratios. Metabolite measures associated with migraine were obtained after single-metabolite logistic regression combined with a random-effects meta-analysis perfo...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Version of record, pdf, 570.0KB)
-
- Publisher copy:
- 10.1212/wnl.0000000000007313
Authors
Bibliographic Details
- Publisher:
- American Academy of Neurology Publisher's website
- Journal:
- Neurology Journal website
- Volume:
- 92
- Issue:
- 16
- Pages:
- e1899-e1911
- Publication date:
- 2019-04-03
- Acceptance date:
- 2018-12-21
- DOI:
- EISSN:
-
1526-632X
- ISSN:
-
0028-3878
- Pmid:
-
30944236
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:999380
- UUID:
-
uuid:651dbaa4-2b86-4679-a90e-9ab8bad81ab1
- Local pid:
- pubs:999380
- Source identifiers:
-
999380
- Deposit date:
- 2019-06-05
Terms of use
- Copyright holder:
- Onderwater, GLJ et al
- Copyright date:
- 2019
- Notes:
- © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record