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Studies related to the metabolism of anabolic steroids in the horse: the metabolism of 1-dehydrotestosterone and the use of fast atom bombardment mass spectrometry in the identification of steroid conjugates.

Abstract:

The metabolism and urinary excretion of 1,2(n)-3H-1-dehydrotestosterone were studied in cross-bred gelded horses. Approximately 40% of the dose was excreted in 24 h. The steroid metabolites were extracted by Amberlite XAD-2 resin and fractionated into glucuronides and sulphoconjugates. Unchanged 1-dehydrotestosterone was the only component identified by gas chromatography mass spectrometry after solvolysis of the sulphoconjugates. Positive and negative ion fast atom bombardment mass spectra w...

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Publication status:
Published

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Publisher copy:
10.1002/bms.1200100709

Authors


Journal:
Biomedical mass spectrometry
Volume:
10
Issue:
7
Pages:
434-440
Publication date:
1983-07-01
DOI:
EISSN:
1096-9888
ISSN:
0306-042X
Source identifiers:
59466
Language:
English
Keywords:
Pubs id:
pubs:59466
UUID:
uuid:6505e93e-3216-45ab-aaed-450e91199fca
Local pid:
pubs:59466
Deposit date:
2012-12-19

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