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Thesis

Establishing modular ligation through transglutaminase engineering

Abstract:

The ability to precisely direct proteins into ordered complexes is highly valuable for the synthetic biologist. Tools that can direct formation of covalent bonds facilitate particularly robust assemblies, which may enable new properties in areas such as optical control or programming of cell behaviour. Decades of research have produced an extensive range of tools for covalent conjugation of proteins both in vitro and in vivo, each with specific requirements and characteristic...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Wolfson College
Role:
Author
ORCID:
0000-0003-2324-9864

Contributors

Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Supervisor
ORCID:
0000-0001-6112-5198


More from this funder
Funder identifier:
https://ror.org/0439y7842
Programme:
Interdisciplinary Biosciences DTP iCASE


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Keywords:
Subjects:
Deposit date:
2024-06-11

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